| Item Type | Name |
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Concept
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Hypotension
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Concept
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Pruritus
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Concept
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Substance P
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Concept
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Inflammation
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Concept
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Hyperalgesia
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Concept
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Diuresis
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|
Concept
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Alzheimer Disease
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Concept
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Neurodegenerative Diseases
|
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Concept
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Monkey Diseases
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Concept
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Dermatitis, Allergic Contact
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Concept
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Dose-Response Relationship, Drug
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Concept
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Hypersensitivity
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|
Concept
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Substance Withdrawal Syndrome
|
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Concept
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Seizures
|
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Concept
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Diabetes Mellitus, Type 2
|
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Concept
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Substance Abuse, Intravenous
|
|
Concept
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Heart Rate
|
|
Concept
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Disease Models, Animal
|
|
Concept
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Substance-Related Disorders
|
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Concept
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Respiratory Insufficiency
|
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Concept
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Blood Pressure
|
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Concept
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Pain
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Concept
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Dermatitis, Atopic
|
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Concept
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Neuralgia
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Concept
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Morphine Dependence
|
|
Concept
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Cocaine-Related Disorders
|
|
Concept
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Opioid-Related Disorders
|
|
Concept
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Structure-Activity Relationship
|
|
Concept
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Gas Gangrene
|
|
Concept
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Hypothermia
|
|
Academic Article
|
Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112.
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Academic Article
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Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/µ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain.
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Academic Article
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The effects of nociceptin/orphanin FQ receptor agonist Ro 64-6198 and diazepam on antinociception and remifentanil self-administration in rhesus monkeys.
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Academic Article
|
Cocaine esterase: interactions with cocaine and immune responses in mice.
|
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Academic Article
|
The role of central gastrin-releasing peptide and neuromedin B receptors in the modulation of scratching behavior in rats.
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|
Academic Article
|
The fate of bacterial cocaine esterase (CocE): an in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination.
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Academic Article
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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.
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Academic Article
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Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys.
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Academic Article
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Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats.
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Academic Article
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The therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability.
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Academic Article
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Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase.
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Academic Article
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Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats.
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Academic Article
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Effects of butorphanol on morphine-induced itch and analgesia in primates.
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Academic Article
|
Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time.
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Academic Article
|
Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats.
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Academic Article
|
Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys.
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|
Academic Article
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The spinal antinociceptive effects of endomorphins in rats: behavioral and G protein functional studies.
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Academic Article
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Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity.
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Academic Article
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Effects of cocaine esterase following its repeated administration with cocaine in mice.
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Academic Article
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PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity.
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|
Academic Article
|
Structural analysis of thermostabilizing mutations of cocaine esterase.
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|
Academic Article
|
Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain.
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|
Academic Article
|
[Dmt1]N/OFQ(1-13)-NH2: a potent nociceptin/orphanin FQ and opioid receptor universal agonist.
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|
Academic Article
|
Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects.
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Academic Article
|
Differential in vivo potencies of naltrexone and 6beta-naltrexol in the monkey.
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Academic Article
|
Antinociceptive, hypothermic, hypotensive, and reinforcing effects of a novel neurotensin receptor agonist, NT69L, in rhesus monkeys.
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Academic Article
|
Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist.
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Academic Article
|
Characterization of scratching responses in rats following centrally administered morphine or bombesin.
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Academic Article
|
Effect of opioid receptor antagonists on hypothalamic-pituitary-adrenal activity in rhesus monkeys.
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Academic Article
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Relative reinforcing effects of three opioids with different durations of action.
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Academic Article
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Comparison of the opioid receptor antagonist properties of naltrexone and 6 beta-naltrexol in morphine-naïve and morphine-dependent mice.
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Academic Article
|
Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats.
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Academic Article
|
Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates.
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Academic Article
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Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys.
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Academic Article
|
Supraspinal actions of nociceptin/orphanin FQ, morphine and substance P in regulating pain and itch in non-human primates.
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|
Academic Article
|
Diltiazem enhances the analgesic but not the respiratory depressant effects of morphine in rhesus monkeys.
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Academic Article
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An experimental itch model in monkeys: characterization of intrathecal morphine-induced scratching and antinociception.
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Academic Article
|
Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats.
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Academic Article
|
Intracisternal nor-binaltorphimine distinguishes central and peripheral kappa-opioid antinociception in rhesus monkeys.
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|
Academic Article
|
The effects of the phyllolitorin analogue [desTrp(3), Leu(8)]phyllolitorin on scratching induced by bombesin and related peptides in rats.
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|
Academic Article
|
Differentiation of kappa opioid agonist-induced antinociception by naltrexone apparent pA2 analysis in rhesus monkeys.
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Academic Article
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kappa-Opioid receptor binding populations in rhesus monkey brain: relationship to an assay of thermal antinociception.
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Academic Article
|
Chronic effects of haloperidol and SCH23390 on operant and licking behaviors in the rat.
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Academic Article
|
A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates.
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|
Academic Article
|
A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates.
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Academic Article
|
Effects of NOP-Related Ligands in Nonhuman Primates.
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|
Academic Article
|
BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates.
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|
Academic Article
|
Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys.
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Academic Article
|
GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn.
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Academic Article
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Antinociceptive, reinforcing, and pruritic effects of the G-protein signalling-biased mu opioid receptor agonist PZM21 in non-human primates.
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|
Academic Article
|
Pleiotropic Effects of Kappa Opioid Receptor-Related Ligands in Non-human Primates.
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Academic Article
|
Nociceptin/Orphanin FQ Peptide Receptor-Related Ligands as Novel Analgesics.
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|
Academic Article
|
Usefulness of the measurement of neurite outgrowth of primary sensory neurons to study cancer-related painful complications.
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|
Academic Article
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Functional consequences of short-term exposure to opioids versus cannabinoids in nonhuman primates.
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Academic Article
|
Potential therapeutic targets for the treatment of opioid abuse and pain.
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Academic Article
|
Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice.
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|
Academic Article
|
Enhanced antidepressant-like effects of a delta opioid receptor agonist, SNC80, in rats under inflammatory pain.
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|
Academic Article
|
Nociceptin Receptor-Related Agonists as Safe and Non-addictive Analgesics.
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